Panaxea International, PaC - 30 Capsules

PaC

30 x 500mg caps

Product Overview

PaC is a combination of herbs that contain proanthocyanidins and phenolic and polyphenolic compounds. These constituents are an important class of secondary plant metabolites. These herbs in combination may act as free radical scavengers supporting conditions resulting from oxidative stress. Phenolic compounds from medicinal herbs and dietary plants possess a range of bioactivities and play an important role in prevention and management of inflammatory disorders.*

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Encourages inhibition of oxidative damage*

Regulates a healthy inflammatory response*

Supports a healthy cellular life cycle* 

Artichoke flower bud ext. (Yang Ji)

References

1. Shahidi.F, Naczk. M: Extraction and analysis of phenolics in food. Journal of Chromatorgraohy, 2004 Oct 29;1054(1-2):95-111.

2. Russell W, Duthie. G. Plant secondary metabolites and gut health: the case for phemolic acids. Proc Nutr Soc. 2011 Aug;70(3):389-96. doi: 10.1017/S0029665111000152.

3. Huang, W Y, Cai, Y Z, Xing, J, Corke, H and Sun, M. 2007. A potential antioxidant resource: endophytic fungi isolated from traditional Chinese medicinal plants. Econ Bot, 61: 14–30.

4. Ueda H, Yamazaki C, Yamazaki M. Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens. Biological & Pharmaceutical Bulletin 2002; 25: 1197-202

Green Tea Leaf Extract (Cha Hua)

References

1.  Cai, Y Z, Sun. M, Xing, J, Luo, Q and Corke, H. 2006. Structure-radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants. Life Sci, 78: 2872–2888. 

2. Surh, Y-J. 2003. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer, 3: 768–780. 

3. Fresco, P, Borges, F, Diniz, C and Marques, M PM. 2006. New insights on the anticancer properties of dietary polyphenols. Med Res Rev, 26: 747–766. 

4. Han, X Z, Shen, T and Lou, H X. 2007. Dietary polyphenols and their biological significance. Int J Mol Sci, 8: 950–988.

5. Chen, C, Yu, R, Owuer, E D and Kong, A N. 2000. Activation of antioxidant response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol compounds during cell survival and death. Arch Pharm Res, 23: 605–612. 

Gingko (Ginkgo biloba) (Ying Xing)

References

1. Wadsworth T L, McDonald T L, Koop D R. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-a. Biochemical Pharmacology 2001; 62: 963-74

Soybean (whole bean) (Dou Chi)

References

1. Cai, Y Z, Luo, Q, Sun, M and Corke, H. 2004. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sci, 74: 2157–2184

2. Atkinson, C, Frankenfeld, CL & Lampe, JW (2005) Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health. Exp Biol Med 230, 155–170. 

Cranberry fruit and seed (Xiao Hong Mei)

References

1. Sartor L, Pezzato E, Dell'Aica I, Caniato R, Biggin S, Garbisa S. Inhibition of matrix-proteases by polyphenols: chemical insights for anti-inflammatory and anti-invasion drug design. Biochemical Pharmacology 2002; 64: 229-37